Wiz - widely-interspaced zinc finger motifs Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 22404
Summary
Enables SET domain binding activity and Histone Methyltransferase binding activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication; protein stabilization; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Orthologous to human WIZ (WIZ zinc finger). [provided by Alliance of Genome Resources, Apr 2022]
Wiz Products (32)
| mRNA | Protein | Name |
|---|---|---|
| NM_001372219.1 | NP_001359148.1 | protein Wiz isoform 4 |
| NM_001372220.1 | NP_001359149.1 | protein Wiz isoform 5 |
| NM_001372221.1 | NP_001359150.1 | protein Wiz isoform 5 |
| NM_001372222.1 | NP_001359151.1 | protein Wiz isoform 6 |
| NM_001372223.1 | NP_001359152.1 | protein Wiz isoform 7 |
| NM_001372224.1 | NP_001359153.1 | protein Wiz isoform 1 |
| NM_001372225.1 | NP_001359154.1 | protein Wiz isoform 8 |
| NM_001372226.1 | NP_001359155.1 | protein Wiz isoform 9 |
| NM_001372227.1 | NP_001359156.1 | protein Wiz isoform 3 |
| NM_001410390.1 | NP_001397319.1 | protein Wiz isoform 15 |
| NM_001410391.1 | NP_001397320.1 | protein Wiz isoform 12 |
| NM_001410392.1 | NP_001397321.1 | protein Wiz isoform 12 |
| NM_001410393.1 | NP_001397322.1 | protein Wiz isoform 7 |
| NM_001410394.1 | NP_001397323.1 | protein Wiz isoform 10 |
| NM_001410395.1 | NP_001397324.1 | protein Wiz isoform 7 |
| NM_001410396.1 | NP_001397325.1 | protein Wiz isoform 7 |
| NM_001410397.1 | NP_001397326.1 | protein Wiz isoform 16 |
| NM_001410398.1 | NP_001397327.1 | protein Wiz isoform 1 |
| NM_001410399.1 | NP_001397328.1 | protein Wiz isoform 8 |
| NM_001410400.1 | NP_001397329.1 | protein Wiz isoform 13 |
| NM_001410401.1 | NP_001397330.1 | protein Wiz isoform 13 |
| NM_001410402.1 | NP_001397331.1 | protein Wiz isoform 19 |
| NM_001410403.1 | NP_001397332.1 | protein Wiz isoform 14 |
| NM_001410404.1 | NP_001397333.1 | protein Wiz isoform 11 |
| NM_001410405.1 | NP_001397334.1 | protein Wiz isoform 20 |
| NM_001410406.1 | NP_001397335.1 | protein Wiz isoform 17 |
| NM_001410407.1 | NP_001397336.1 | protein Wiz isoform 11 |
| NM_001410408.1 | NP_001397337.1 | protein Wiz isoform 14 |
| NM_001410409.1 | NP_001397338.1 | protein Wiz isoform 21 |
| NM_001410410.1 | NP_001397339.1 | protein Wiz isoform 18 |
| NM_011717.5 | NP_035847.2 | protein Wiz isoform 2 |
| NM_212438.4 | NP_997603.3 | protein Wiz isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables SET domain binding |
IPI
IPI: Inferred from physical interaction
|
16702210 | MGI |
| enables histone methyltransferase binding |
IPI
IPI: Inferred from physical interaction
|
16702210 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16702210 | MGI |
| enables protein-containing complex binding |
IDA
IDA: Inferred from direct assay
|
16702210 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| NOT located in nucleolus |
IDA
IDA: Inferred from direct assay
|
16702210 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
16702210 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein Wiz |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(18)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-159099 | WIZ degrader 9 | Degrader | 99.29% | Unkown |
| HY-175742 | BMS-986470 | Degrader | 99.78% | Unkown |
| HY-169761B | (R,R)-dWIZ-1 TFA | Control | 98.58% | Unkown |
| HY-169955A | WIZ degrader 8 TFA | Degrader | 99.41% | Unkown |
| HY-159098 | dWIZ-1 | Degrader | / | Unkown |
| HY-169955 | WIZ degrader 8 | Degrader | 98.30% | Unkown |
| HY-175742A | (R)-BMS-986470 | 99.93% | Unkown | |
| HY-163820 | WIZ degrader 4 | Degrader | 99.37% | Unkown |
| HY-162665 | WIZ degrader 1 | Inducer | / | Unkown |
| HY-163818 | WIZ degrader 2 | Degrader | / | Unkown |
| HY-163819 | WIZ degrader 3 | Degrader | / | Unkown |
| HY-169761 | (rac)-dWIZ-1 | Degrader | / | Unkown |
| HY-RS15821 | WIZ Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-163822 | WIZ degrader 5 | Degrader | / | Unkown |
| HY-163823 | WIZ degrader 6 | Degrader | / | Unkown |
| HY-163824 | WIZ degrader 7 | Degrader | / | Unkown |
| HY-RS22086 | Wiz Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28606 | Wiz Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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