WIZ degrader 1
WIZ degrader 1 is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders.
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- No. CAS: 2839552-68-8
- Fòrmula: C25H33F2N5O2
- Peso molecular:473.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
WIZ degrader 1 (Compound 141) degrades WIZ in 293T cells with an AC50 of 2 nMsup>[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2839552-68-8
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Peso molecular 473.56
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Fòrmula C25H33F2N5O2
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SMILES
FC1(F)CCC(CN2CC[C@@H](CC3=CC4=C(N5CCC(NC5=O)=O)C=NN4C=C3)C[C@@H]2C)CC1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)