2839552-68-8
Chemical Structure
WIZ degrader 1
- CAS No.: 2839552-68-8
- Formula:C25H33F2N5O2
- Molecular Weight:473.56
InChIKey: QWAVXZLEKWIWKO-PKOBYXMFSA-N
SMILES: FC1(F)CCC(CN2CC[C@@H](CC3=CC4=C(N5CCC(NC5=O)=O)C=NN4C=C3)C[C@@H]2C)CC1
Biological Activity: WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders[1].
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WIZ degrader 1 | WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders. | |||||||||||||||||||||
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Keywords