WIZ - WIZ zinc finger Gene

Homo sapiens

Also known as ZNF803

Gene ID: 58525 | Gene type: protein coding

About WIZ

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:15,419,978-15,449,956 (from NCBI)

This gene has 12 transcripts (splice variants), 263 orthologues and 51 paralogues. Ubiquitous expression in testis (RPKM 8.9), fat (RPKM 6.6) and 25 other tissues.

Summary

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; Histone Methyltransferase binding activity; and transcription corepressor binding activity. Involved in positive regulation of nuclear cell cycle DNA replication and protein stabilization. Located in midbody and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

WIZ Products(5)

mRNA	Protein	Name
NM_001330395.4	NP_001317324.2	protein Wiz isoform 2
NM_001371589.1	NP_001358518.1	protein Wiz isoform 3
NM_001371603.5	NP_001358532.2	protein Wiz isoform 4
NM_001411129.1	NP_001398058.1	protein Wiz isoform 5
NM_021241.3	NP_067064.2	protein Wiz isoform 1

WIZ Protein Structure

zf-C2H2_4

0
200
400
600
794 a.a.

Protein Preferred Names

Protein Names

protein Wiz

widely interspaced zinc finger motifs

Related Diseases

Diseases

Alias

Autosomal Dominant Wolfram Syndrome

Kleefstra Syndrome

9q34.3 Microdeletion Syndrome	9q Subtelomeric Deletion Syndrome
9q- Syndrome	Chromosome 9q Deletion Syndrome
9q34.3 Deletion Syndrome	9qstds
Chromosome 9q34.3 Deletion Syndrome	Chromosome 9, Trisomy 9q

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15821	WIZ Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	WIZ	VGNC	VGNC:79901
Canis familiaris	WIZ	VGNC	VGNC:106618
Mus musculus	WIZ	MGD	MGI:1332638
Bos taurus	WIZ	VGNC	VGNC:36947
Rattus norvegicus	WIZ	RGD	RGD:1307771
Felis catus	WIZ	VGNC	VGNC:80758