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Cat. No.: HY-163823

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WIZ degrader 6

WIZ degrader 6 (compound 10) is a WIZ degrader with the EC₅₀ of ＜0.01μM. WIZ degrader 6 can be used for study of sickle cell disease.

For research use only. We do not sell to patients.

CAS No.: 3036553-87-1
Formula: C₂₈H₂₂FN₅O₅
Molecular Weight:527.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

WIZ degrader 6 Chemical Structure

CAS No.: 3036553-87-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

WIZ degrader 6 (compound 10) is a WIZ degrader with the EC₅₀ of ＜0.01μM. WIZ degrader 6 can be used for study of sickle cell disease^[1].

All Histone Acetyltransferase Isoforms :

Chemical Information

CAS No. 3036553-87-1
Molecular Weight 527.50
Formula C₂₈H₂₂FN₅O₅
SMILES

O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(NC4=C(C=NN5C)C5=CC=C4OC6=C(C)C=CC=C6F)=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. InventorThomas J, et al. Compounds and their use for treatment of hemoglobinopathies. WO2024097932A1. 2024-05-10.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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