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Cat. No.: HY-163824

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WIZ degrader 7

WIZ degrader 7 (Example 16) is a WIZ degrader with an IC₅₀ value of < 0.01 μM. WIZ degrader 7 can be used to investigate sickle cell disease (SCD) and thalassemia.

For research use only. We do not sell to patients.

CAS No.: 3036553-83-7
Formula: C₂₉H₂₄N₆O₄
Molecular Weight:520.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

WIZ degrader 7 Chemical Structure

CAS No.: 3036553-83-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

WIZ degrader 7 (Example 16) is a WIZ degrader with an IC₅₀ value of < 0.01 μM. WIZ degrader 7 can be used to investigate sickle cell disease (SCD) and thalassemia^[1].

All Histone Acetyltransferase Isoforms :

Chemical Information

CAS No. 3036553-83-7
Molecular Weight 520.54
Formula C₂₉H₂₄N₆O₄
SMILES

O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(NC4=CC5=C(C=C4C6=CC(C)=NC=C6)N=CN5C7CC7)=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thomas J, et al. Compounds and their use for treatment of hemoglobinopathies. WO2024097932A1.2024-05-10.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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