FLG - Flg filaggrin Gene

Also Known as Pflg

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24641

Summary

Predicted to enable keratin filament binding activity. Predicted to be a structural constituent of skin epidermis. Involved in epidermal cell differentiation. Predicted to be located in cornified envelope; cytoplasmic ribonucleoprotein granule; and keratohyalin granule. Human ortholog(s) of this gene implicated in atopic dermatitis 2 and ichthyosis vulgaris. Orthologous to human FLG (filaggrin). [provided by Alliance of Genome Resources, Apr 2022]

FLG Products (1)

mRNA Protein Name
NM_001393766.1 NP_001380695.1 filaggrin

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epidermal cell differentiation IMP
IMP: Inferred from mutant phenotype
7688400 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

filaggrin

  • Filaggrin (profilaggrin)

  • profilaggrin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-14844 Lagociclovir Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04911 FGFR1 Human Pre-designed siRNA Set A / Unkown
HY-RS04912 Fgfr1 Mouse Pre-designed siRNA Set A / Unkown
HY-P10779 flg22Pst Inhibitor / Unkown
HY-RS04975 FLG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04976 FLG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18589 Flg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25074 Flg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FLG NCBI NCBI:2312