Tnfsf15 - TNF superfamily member 15 Gene

Also Known as Tnlg1b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 252878

Summary

Enables death receptor binding activity. Involved in activation of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of cytokine production. Predicted to be located in plasma membrane. Orthologous to human TNFSF15 (TNF Superfamily member 15). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf15 Products (1)

mRNA Protein Name
NM_145765.2 NP_665708.1 tumor necrosis factor ligand superfamily member 15

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables death receptor binding IDA
IDA: Inferred from direct assay
11911831 RGD
Biological Process GO Annotation Evidence References Source
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
11911831 RGD
involved in positive regulation of cytokine production IDA
IDA: Inferred from direct assay
11911831 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 15

  • TNF ligand-related molecule 1

  • tumor necrosis factor (ligand) superfamily, member 15

  • tumor necrosis factor ligand 1b

  • tumor necrosis factor superfamily member 15

  • vascular endothelial cell growth inhibitor

Recombinant Tnfsf15 Proteins

Cat. No. Product Name Accession Purity
HY-P74508 TL1A/TNFSF15 Protein, Rat (HEK293, Fc) Q8K3Y7 (D94-I252) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990007 Tulisokibart Inhibitor 99.00% Phase 3
HY-P990006 Duvakitug Inhibitor 99.76% Phase 3

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14826 TNFSF15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17391 Tnfsf15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23846 Tnfsf15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990151 Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) Inhibitor 95.00% Unkown
HY-P991440 AMG-966 Inhibitor 98.38% Unkown
HY-P992444 PR200 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf15 NCBI NCBI:9966