S1PR1 - sphingosine-1-phosphate receptor 1 Gene

Bos taurus

Also known as EDG1; S1P1

Gene ID: 281135 | Gene type: protein coding

About S1PR1

Primary_assembly 3: 42,027,458-42,039,822 reverse strand.ARS-UCD1.2:CM008170.2

This gene has 2 transcripts (splice variants), 199 orthologues and 19 paralogues.

mRNA	Protein	Name
NM_001013585.4	NP_001013603.2	sphingosine 1-phosphate receptor 1

7tmA_S1PR1_Edg1

Protein Preferred Names

Protein Names

sphingosine 1-phosphate receptor 1

S1P receptor 1	S1P receptor Edg-1
endothelial differentiation G-protein coupled receptor 1	endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
sphingosine 1-phosphate receptor Edg-1

Approval

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12355	Siponimod	Agonist	99.95%	Yes
HY-12288	Ozanimod	Agonist	99.98%	Yes
HY-10569	Ponesimod	Agonist	99.78%	Yes
HY-12288A	Ozanimod hydrochloride	Modulator	98.10%	Yes
HY-12355A	Siponimod hemifumarate	Agonist	99.64%	Yes

Clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-17606	Cenerimod	Agonist	99.43%	Phase 3
HY-109038	Mocravimod	Modulator	98.39%	Phase 3
HY-132847	Vibozilimod	Agonist	99.52%	Phase 2
HY-115831	SAR247799	Agonist	99.38%	Phase 1
HY-14976	CS-0777	Modulator	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (19)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W008947	SEW2871	Agonist	99.88%	Unkown
HY-111253	CYM-5478	Agonist	99.90%	Unkown
HY-136578	RP101988	Agonist	98.80%	Unkown
HY-176533	S1PR5-IN-1	Inhibitor	99.58%	Unkown
HY-158417	KSI-6666	Antagonist	96.15%	Unkown
HY-136576	RP101075	Agonist	99.19%	Unkown
HY-147660	IMMH001	Agonist	98.10%	Unkown
HY-113934	L-threo Lysosphingomyelin (d18:1)	Agonist	98.0%	Unkown
HY-120615	BMS-520	Agonist	/	Unkown
HY-108492	TC-SP 14	Agonist	/	Unkown
HY-14402	AMG 369	Agonist	/	Unkown
HY-136577	RP101442	Agonist	/	Unkown
HY-183578	TYY-31	Agonist	/	Unkown
HY-119245	Udifitimod	Modulator	/	Unkown
HY-178491	S1PR1 agonist 3	Agonist	/	Unkown
HY-182626	CS1P1	Antagonist	/	Unkown
HY-182375	(R)-SLB1122168 free base	Inhibitor	/	Unkown
HY-181875	S1PR1/S1PR5 agonist-1	Inhibitor	/	Unkown
HY-182960	KRP-203 monophosphate		/	Unkown

Species	Symbol	Source	ID
Homo sapiens	S1PR1	NCBI	NCBI:1901

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