S1PR1 - sphingosine-1-phosphate receptor 1 Gene

Also Known as EDG1; S1P1

Species: Bos taurus

Gene Type: protein coding
Gene ID: 281135

About S1PR1

Primary_assembly 3: 42,027,458-42,039,822 reverse strand.ARS-UCD1.2:CM008170.2

This gene has 2 transcripts (splice variants), 199 orthologues and 19 paralogues.

S1PR1 Products (1)

mRNA Protein Name
NM_001013585.4 NP_001013603.2 sphingosine 1-phosphate receptor 1

S1PR1 Protein Structure

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (45 - 321)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (46 - 72)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (79 - 104)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (116 - 146)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (157 - 177)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (197 - 226)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (248 - 278)

7tmA_S1PR1_Edg1

7tmA_S1PR1_Edg1: cd15346 (289 - 314)

  • 0
  • 100
  • 200
  • 300
  • 382 a.a.
Protein Preferred Names Protein Names

sphingosine 1-phosphate receptor 1

  • S1P receptor 1

  • S1P receptor Edg-1

  • endothelial differentiation G-protein coupled receptor 1

  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1

  • sphingosine 1-phosphate receptor Edg-1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12355 Siponimod Agonist 99.95% Yes
HY-12288 Ozanimod Agonist 99.98% Yes
HY-10569 Ponesimod Agonist 99.78% Yes
HY-12288A Ozanimod hydrochloride Modulator 98.10% Yes
HY-12355A Siponimod hemifumarate Agonist 99.64% Yes

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-17606 Cenerimod Agonist 99.43% Phase 3
HY-109038 Mocravimod Modulator 98.39% Phase 3
HY-132847 Vibozilimod Agonist 99.52% Phase 2
HY-115831 SAR247799 Agonist 99.38% Phase 1
HY-14976 CS-0777 Modulator / Phase 1

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W008947 SEW​2871 Agonist 99.88% Unkown
HY-111253 CYM-5478 Agonist 99.90% Unkown
HY-136578 RP101988 Agonist 98.80% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-158417 KSI-6666 Antagonist 96.15% Unkown
HY-136576 RP101075 Agonist 99.19% Unkown
HY-147660 IMMH001 Agonist 98.10% Unkown
HY-113934 L-threo Lysosphingomyelin (d18:1) Agonist 98.0% Unkown
HY-14433 PF-462991 Agonist / Unkown
HY-120615 BMS-520 Agonist / Unkown
HY-136577 RP101442 Agonist / Unkown
HY-183578 TYY-31 Agonist / Unkown
HY-181875 S1PR1/S1PR5 agonist-1 Inhibitor / Unkown
HY-119245 Udifitimod Modulator / Unkown
HY-178491 S1PR1 agonist 3 Agonist / Unkown
HY-108492 TC-SP 14 Agonist / Unkown
HY-182626 CS1P1 Antagonist / Unkown
HY-14402 AMG 369 Agonist / Unkown
HY-182375 (R)-SLB1122168 free base Inhibitor / Unkown
HY-182960 KRP-203 monophosphate / Unkown
HY-18334 GSK-2262167 sodium Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S1PR1 NCBI NCBI:1901