HUNK - hormonally up-regulated Neu-associated kinase Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 30811

About HUNK

Cytogenetic location: 21q22.11 Genomic coordinates (GRCh38): 21:31,873,020-32,004,064 (from NCBI)

This gene has 4 transcripts (splice variants), 158 orthologues and 17 paralogues. Broad expression in placenta (RPKM 1.4), colon (RPKM 1.2) and 20 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

HUNK Products (1)

mRNA Protein Name
NM_014586.2 NP_055401.1 hormonally up-regulated neu tumor-associated kinase

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20133759 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HUNK Protein Structure

Pkinase

Pkinase: Protein kinase domain (66 - 320)

  • 0
  • 200
  • 400
  • 600
  • 714 a.a.
Protein Preferred Names Protein Names

hormonally up-regulated neu tumor-associated kinase

  • B19

HUNK Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HUNK P57058 LIMK1 Homo sapiens P53667
Anti Bait CoIP
20133759
Intra
HUNK P57058 LIMK1 Homo sapiens P53667
Y2H Fragment Pooling
35914814
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Recombinase Activating Gene 1 Deficiency
Immunodeficiency 39

  • IMD39

  • Immunodeficiency, Type 39
Combined Cellular And Humoral Immune Defects With Granulomas

  • Combined Immunodeficiency With Skin Granulomas

  • CCHIDG

  • Cid Due To Rag 1/2 Deficiency

  • Combined Immunodeficiency Due To Rag 1/2 Deficiency

  • Combined Immunodeficiency With Granulomatosis

  • CHIDG

  • Immune Defects, Combined Cellular And Humoral With Granulomas
Immunodeficiency 44

  • IMD44
Baylisascariasis

  • Infection By Baylisascaris
Immunodeficiency 31b

  • IMD31B

  • Immunodeficiency 31b, Mycobacterial And Viral Infections, Autosomal Recessive

  • Autosomal Recessive Stat1 Deficiency

  • Predisposition To Severe Viral Infection Due To Stat1 Deficiency

  • Susceptibility To Viral And Mycobacterial Infections Due To Stat1 Deficiency

  • Stat1 Deficiency, Autosomal Recessive

  • Autosomal Recessive Immunodeficiency 31b, Mycobacterial And Viral Infections

  • Stat1 Deficiency

  • Autosomal Recessive Susceptibility To Mycobacterial And Viral Infections

  • Mycobacterial And Viral Infections Due To Complete Stat1 Deficiency

  • Immunodeficiency, Type 31b, Mycobacterial And Viral Infections, Autosomal Recessive
Cataract 18

  • Cataract, Autosomal Recessive Congenital 2

  • Catc2

  • CTRCT18

  • Autosomal Recessive Congenital Cataract 2

  • Cataract 18, Autosomal Recessive

  • Cataract 18 Autosomal Recessive

  • Cataract, Type 18
Cataract 44

  • CTRCT44

  • Total Early-Onset Cataract

  • Cataract 44 And Hypotrichosis

  • Cataract And Hypotrichosis

  • Cataract, Type 44
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS06491 HUNK Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HUNK RGD RGD:1565091
Bos taurus HUNK VGNC VGNC:49999
Felis catus HUNK VGNC VGNC:62858
Canis familiaris HUNK VGNC VGNC:53027
Mus musculus HUNK MGD MGI:1347352
Macaca mulatta HUNK VGNC VGNC:73386
Others HUNK NCBI