Adipor2 - adiponectin receptor 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312670

Summary

Predicted to enable adipokinetic hormone receptor activity; Adiponectin binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of hepatic stellate cell migration; positive regulation of glucose import; and response to fructose. Predicted to be intrinsic component of plasma membrane. Predicted to be active in plasma membrane. Biomarker of end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); and obesity. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease and type 2 diabetes mellitus. Orthologous to human ADIPOR2 (Adiponectin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Adipor2 Products (1)

mRNA Protein Name
NM_001037979.1 NP_001033068.1 adiponectin receptor protein 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to fatty acid IEP
IEP: Inferred from expression pattern
21194380 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
15855268 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
15754086 RGD
involved in negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
16415076 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
29237572 RGD
involved in negative regulation of hepatic stellate cell migration IMP
IMP: Inferred from mutant phenotype
29237572 RGD
involved in positive regulation of D-glucose import IMP
IMP: Inferred from mutant phenotype
17569760 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
29237572 RGD
involved in response to amine IEP
IEP: Inferred from expression pattern
17696487 RGD
involved in response to bacterium IEP
IEP: Inferred from expression pattern
23797890 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
23838384 RGD
involved in response to fructose IEP
IEP: Inferred from expression pattern
23797890 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
23838384 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16483885 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
17006986 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
26115886 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adiponectin receptor protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15848 AdipoRon Agonist 99.88% Unkown
HY-N0166 Gramine 99.80% Unkown
HY-110164 AdipoRon hydrochloride Agonist 99.80% Unkown
HY-N0166R Gramine (Standard) 98.95% Unkown
HY-15848R AdipoRon (Standard) Agonist / Unkown
HY-RS00380 ADIPOR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N0166S Gramine-d2 / Unkown
HY-RS21981 Adipor2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28498 Adipor2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adipor2 NCBI NCBI:79602