WDR5 - Wdr5 WD repeat domain 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362093

Summary

Predicted to enable methylated histone binding activity. Predicted to contribute to Histone Methyltransferase activity (H3-K4 specific). Involved in neuron projection development. Located in nucleus. Orthologous to human WDR5 (WD repeat domain 5). [provided by Alliance of Genome Resources, Apr 2022]

WDR5 Products (1)

mRNA Protein Name
NM_001039034.1 NP_001034123.1 WD repeat-containing protein 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15860628 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron projection development IDA
IDA: Inferred from direct assay
21816345 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat-containing protein 5

  • WD repeat-containing protein 5-like

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-100869A MM-589 TFA Inhibitor 98.67% Phase 3
HY-16994 OICR-0547 Inhibitor 99.85% Phase 1

Pre-clinical Phase

Bioactive Molecules (56)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16993 OICR-9429 Inhibitor 99.71% Unkown
HY-141796 MS67 Degrader 99.12% Unkown
HY-12220 MM-102 Inhibitor 99.09% Unkown
HY-19347 WDR5-0103 Antagonist 99.94% Unkown
HY-150654 WDR5-IN-5 Inhibitor 99.56% Unkown
HY-19554A MM-401 TFA Inhibitor 99.34% Unkown
HY-133121 WDR5-IN-1 Inhibitor 98.0% Unkown
HY-12220A MM-102 TFA Inhibitor 99.68% Unkown
HY-141799 Dimethyl-F-OICR-9429-COOH Ligand 98.11% Unkown
HY-154949 WDR5-IN-6 Inhibitor 99.83% Unkown
HY-153728 WM-586 Inhibitor 98.71% Unkown
HY-111753 WDR5-IN-4 Inhibitor 98.13% Unkown
HY-111753A WDR5-IN-4 TFA Inhibitor 98.04% Unkown
HY-154847 WM-662 Inhibitor 99.48% Unkown
HY-N1983 Caudatin 99.95% Unkown
HY-149873 Anticancer agent 126 Inhibitor 98.05% Unkown
HY-153331 DDO-2213 Inhibitor 98.84% Unkown
HY-157332 WDR5-IN-7 Inhibitor 98.75% Unkown
HY-162014 WDR5 degrader-1 Degrader 98.00% Unkown
HY-175802 HBI-2375 Inhibitor 98.06% Unkown
HY-P10948A CS-VIP 8 hydrochloride Inhibitor 96.04% Unkown
HY-141797 MS33 Degrader 99.38% Unkown
HY-148817 WDR5-0102 Inhibitor 97.07% Unkown
HY-100869 MM-589 Inhibitor / Unkown
HY-132233 DDO-2093 Inhibitor / Unkown
HY-141798 OICR-9429-N-C2-NH2 Ligand / Unkown
HY-150403 XF067-68 Degrader 99.56% Unkown
HY-100869B MM-589 (racemic mixture ) TFA Inhibitor 99.83% Unkown
HY-N1983R Caudatin (Standard) 99.31% Unkown
HY-153728A (R)-WM-586 Inhibitor 99.07% Unkown
HY-157659 WDR5-47 Antagonist 98.34% Unkown
HY-168487 PROTAC WDR5 degrader 1 Inhibitor / Unkown
HY-169389 OICR41114 Degrader / Unkown
HY-163774 WDR5-MYC-IN-1 Inhibitor / Unkown
HY-179099 WDR5 probe 1 / Unkown
HY-P10948 CS-VIP 8 Inhibitor / Unkown
HY-148829 MS40 Degrader / Unkown
HY-183959 DC_M5_2 Inhibitor / Unkown
HY-172196 LH168 / Unkown
HY-RS15785 WDR5 Human Pre-designed siRNA Set A Degrader / Unkown
HY-161123 WDR5-IN-8 Inhibitor / Unkown
HY-174255 WDR5-MYC-IN-2 Inhibitor / Unkown
HY-19554 MM-401 Inhibitor / Unkown
HY-159993 MR44397 Inhibitor / Unkown
HY-150400A XF056-132 Degrader / Unkown
HY-169415 DBL-6-13 Inhibitor / Unkown
HY-181972 PROTAC WDR5 degrader 2 Degrader / Unkown
HY-183354 HLC40 / Unkown
HY-168475 DD0-2363 Inhibitor / Unkown
HY-175754 C3TD078 Inhibitor / Unkown
HY-178751 Z116334910 Inhibitor 99.32% Unkown
HY-181973 WDR5 ligand 3 Ligand / Unkown
HY-178752 Z88418521 Ligand / Unkown
HY-RS15789 WDR5B Human Pre-designed siRNA Set A Degrader / Unkown
HY-150400 XF056-132 free base Degrader / Unkown
HY-168488 WDR5 ligand 2 Ligand / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens WDR5 NCBI NCBI:11091