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Cat. No.: HY-181973

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WDR5 ligand 3

WDR5 ligand 3 is a WDR5 ligand that can be used for the synthesis of PORTACs, such as PROTAC WDR5 degrader 2 (HY-181972).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₄H₃₆F₄N₆O₃
분자량:652.68

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

WDR5 ligand 3 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

WDR5 ligand 3 is a WDR5 ligand that can be used for the synthesis of PORTACs, such as PROTAC WDR5 degrader 2 (HY-181972)^[1].

Chemical Information

분자량 652.68
화학식 C₃₄H₃₆F₄N₆O₃
SMILES

C#CCN1CCN(CC1)C(C2=CC=C(C(C3=CC(NC(C(C(C(F)(F)F)=C4)=CNC4=O)=O)=C(N5C[C@@H](N([C@@H](C5)C)C)C)C=C3)=C2)F)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Lu H, et al. Design, Synthesis and Biological Evaluation of Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors. J Med Chem. 2025;68(23):25011-25025. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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