DDX19A - DEAD-box helicase 19A Gene

Also Known as DDX19L; DDX19-DDX19L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55308

About DDX19A

This gene has 15 transcripts (splice variants), 243 orthologues and 38 paralogues. Ubiquitous expression in thyroid (RPKM 14.8), placenta (RPKM 14.0) and 25 other tissues.

Summary

Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

DDX19A Products (5)

mRNA Protein Name
NM_001320522.2 NP_001307451.1 ATP-dependent RNA helicase DDX19A isoform 2
NM_001320525.2 NP_001307454.1 ATP-dependent RNA helicase DDX19A isoform 3
NM_001320526.2 NP_001307455.1 ATP-dependent RNA helicase DDX19A isoform 4
NM_001320527.2 NP_001307456.1 ATP-dependent RNA helicase DDX19A isoform 5
NM_018332.5 NP_060802.1 ATP-dependent RNA helicase DDX19A isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX19A Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (116 - 280)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (351 - 433)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 478 a.a.
Protein Preferred Names Protein Names

ATP-dependent RNA helicase DDX19A

  • DDX19-like protein

DDX19A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DDX19A Q9NUU7 CTIF Homo sapiens O43310-2
Y2H Prey Pooling
32296183
Intra
DDX19A Q9NUU7 CTIF Homo sapiens O43310-2
Y2H Array
32296183
Intra
DDX19A Q9NUU7 CTIF Homo sapiens O43310-2
Anti Tag CoIP
28514442
Intra
DDX19A Q9NUU7 CFTR Homo sapiens P13569
Ub Reconstruction
35156780
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Y2H Array
31515488
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Anti Tag CoIP
33961781
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Validated Y2H
25416956
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Anti Tag CoIP
28514442
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Y2H Array
25416956
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6
Y2H Pooling
16189514
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6-2
Y2H Array
32296183
Intra
DDX19A Q9NUU7 MIF4GD Homo sapiens A9UHW6-2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant DDX19A Proteins

Cat. No. Product Name Accession Purity
HY-P71651 DDX19A Protein, Human (His-SUMO) Q9NUU7-1 (M1-N478) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03634 DDX19A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19058 Ddx19a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25548 Ddx19a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DDX19A VGNC VGNC:53331
Rattus norvegicus DDX19A RGD RGD:1303136
Bos taurus DDX19A VGNC VGNC:52191
Mus musculus DDX19A MGD MGI:99526