Adipor2 - adiponectin receptor 2 Gene

Enables Adiponectin binding activity; identical protein binding activity; and signaling receptor activity. Involved in glucose homeostasis; positive regulation of cold-induced thermogenesis; and vascular wound healing. Acts upstream of or within adiponectin-activated signaling pathway. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease and type 2 diabetes mellitus. Orthologous to human ADIPOR2 (Adiponectin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]