2. Gene
  3. ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ACS; PHACS

Gene ID: 84680 | Gene type: protein coding

About ACCS

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:44,066,270-44,084,237 (from NCBI)

This gene has 13 transcripts (splice variants), 149 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 11.2), gall bladder (RPKM 7.3) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]

ACCS Products(2)

mRNA Protein Name
NM_001127219.2 NP_001120691.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1
NM_032592.4 NP_115981.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1

ACCS Protein Structure

Aminotran_1_2

Aminotran_1_2: Aminotransferase class I and II (98 - 460)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 501 a.a.
Protein Preferred Names Protein Names

1-aminocyclopropane-1-carboxylate synthase-like protein 1

ACC synthase-like protein 1

Related Diseases

Diseases Alias
Thyroid Dyshormonogenesis 5

TDH5

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 5

Thyroid Hormonogenesis, Genetic Defect In, 5

Genetic Defect In Thyroid Hormonogenesis 5

Chdh5

Congenital Hypothyroidism Due To Dyshormonogenesis Type 5

Genetic Defect In Thyroid Hormonogenesis Type 5
Granulomatous Amebic Encephalitis

Granulomatous Amoebic Encephalitis

Acanthamoeba Encephalitis

Acanthamoeba Granulomatous Encephalitis

Granulomatous Amebic Encephalitis Due To Acanthamoeba
Twin-To-Twin Transfusion Syndrome

Twin To Twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin

Fetal Hemorrhage Into Co-Twin

Twin To Twin Transfusion

Twin-To-Twin Blood Transfer

Fetal Transfusion Syndrome

Fetofetal Transfusion Syndrome

Ttts

Feto-Fetal Transfusion Syndrome

Fetofetal Transfusion

Fetus-To-Fetus Placental Transfusion Syndrome
Primary Amebic Meningoencephalitis

Pam

Naegleria Fowleri Infection

Meningoencephalitis Caused By Naegleria Fowleri

Primary Amoebic Meningoencephalitis
Thyroid Dyshormonogenesis 4

Deiodinase Deficiency

TDH4

Iodotyrosine Dehalogenase Deficiency

Thyroid Hormonogenesis, Genetic Defect In, 4

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 4

Genetic Defect In Thyroid Hormonogenesis 4

Chdh4

Congenital Hypothyroidism Due To Dyshormonogenesis Type 4

Genetic Defect In Thyroid Hormonogenesis Type 4
Aplasia Of Lacrimal And Salivary Glands

ALSG

Congenital Absence Of Lacrimal Puncta And Salivary Glands

Xerostomia

Absence Of Salivary Glands

Parotid Aplasia Or Hypoplasia

Congenital Absence Of Lacrimal Puncta Or Salivary Glands

Alsg - [Aplasia Of Lacrimal Or Salivary Glands]
Mucopolysaccharidosis, Type Ix

Mucopolysaccharidosis Type Ix

Hyaluronidase Deficiency

MPS9

Mps Ix

Mucopolysaccharidosis Ix

Mpsix

Mucopolysaccharidosis Type 9

Mucopolysaccharidosis 9
Neonatal Anemia

Anemia Neonatal

Anemia, Neonatal

Anaemia Neonatal

Neonatal Anaemia
Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-17641 Olumacostat glasaretil Inhibitor 98.90% Phase 3
HY-16901 Firsocostat Inhibitor 99.96% Phase 2
HY-12942 PF-05175157 Inhibitor 98.46% Phase 2
HY-107709 MK-4074 Inhibitor 99.04% Phase 1
HY-102066 Utatrectinib Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (30)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101842 ND-646 Inhibitor 99.53% Unkown
HY-D0713 7ACC2 Inhibitor 99.62% Unkown
HY-135981 CMS-121 Inhibitor 99.63% Unkown
HY-D0067 7ACC1 Inhibitor 99.96% Unkown
HY-12741 LDN-212320 Activator 99.09% Unkown
HY-15259A CP-640186 hydrochloride Inhibitor 99.90% Unkown
HY-15259 CP-640186 Inhibitor 99.72% Unkown
HY-153367 FHD-609 Inhibitor 99.15% Unkown
HY-152117 Acetyl-CoA Carboxylase-IN-1 Inhibitor 99.16% Unkown
HY-147004 A-908292 Inhibitor 99.37% Unkown
HY-100771 PCC0208009 Inhibitor 99.08% Unkown
HY-144701 SABA1 Inhibitor 99.15% Unkown
HY-120904 AMPK-IN-1 Activator / Unkown
HY-16901A Firsocostat (S enantiomer) 98.14% Unkown
HY-19624 NVP-ACC789 Inhibitor 99.94% Unkown
HY-147376 hACC2-IN-1 Inhibitor / Unkown
HY-147930 ACC1/2-IN-1 Inhibitor / Unkown
HY-147932 ACC1/2-IN-2 Inhibitor / Unkown
HY-148684 AMPK activator 10 Activator / Unkown
HY-151931 JA-ACC / Unkown
HY-151931S JA-ACC-d3 / Unkown
HY-E70227 Cathepsin G, human neutrophils / Unkown
HY-P10002 EWFW-ACC / Unkown
HY-P10002A EWFW-ACC TFA / Unkown
HY-P10003 iso-VQA-ACC / Unkown
HY-P10003A iso-VQA-ACC TFA / Unkown
HY-RS00146 ACCS Human Pre-designed siRNA Set A / Unkown
HY-16943 Moiramide B / Unkown
HY-16944 Soraphen A / Unkown
HY-16946 CP-610431 / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ACCS RGD RGD:1309314
Mus musculus ACCS MGD MGI:1919717