ACC1/2-IN-2
Based on 1 Customer Validation
ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 has antiproliferation activity and can be used for cancer research.
For research use only. We do not sell to patients.
- Purity: 99.00%
- CAS No.: 1031411-94-5
- Formula: C24H25N3O3
- Molecular Weight:403.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
48 nM
Compound: 1
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Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by fluorescence assay
Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by fluorescence assay
|
[PMID: 22148323] |
| CHO | IC50 |
48 nM
Compound: 17
|
Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence reader
Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence reader
|
[PMID: 20219367] |
Chemical Information
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CAS No. 1031411-94-5
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Appearance Solid
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Molecular Weight 403.47
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Formula C24H25N3O3
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Color White to off-white
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SMILES
O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)