ACC1/2-IN-2
Based on 1 Customer Validation
ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 has antiproliferation activity and can be used for cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.00%
- No. CAS: 1031411-94-5
- Fòrmula: C24H25N3O3
- Peso molecular:403.47
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
48 nM
Compound: 1
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Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by fluorescence assay
Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by fluorescence assay
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[PMID: 22148323] |
| CHO | IC50 |
48 nM
Compound: 17
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Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence reader
Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence reader
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[PMID: 20219367] |
Chemical Information
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No. CAS 1031411-94-5
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Appearance Solid
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Peso molecular 403.47
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Fòrmula C24H25N3O3
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Color White to off-white
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SMILES
O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)