ACC1/2-IN-3
ACC1/2-IN-3 (example 66) is an ACC1 and ACC2 inhibitor with an IC50 value of 1-10 nM for both. ACC1/2-IN-3 can be used for the study of diseases mediated by ACC, such as metabolic disease.
For research use only. We do not sell to patients.
- CAS No.: 2131091-32-0
- Formula: C32H39N3O8S
- Molecular Weight:625.73
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2131091-32-0
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Appearance Solid
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Molecular Weight 625.73
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Formula C32H39N3O8S
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Color White to light yellow
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SMILES
O=C(OC(C)(C)C)C(C)(C)N(C(N(C[C@@H](C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC=CO5)S3)=O)C4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (79.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5981 mL | 7.9907 mL | 15.9813 mL | 39.9533 mL |
| 5 mM | 0.3196 mL | 1.5981 mL | 3.1963 mL | 7.9907 mL | |
| 10 mM | 0.1598 mL | 0.7991 mL | 1.5981 mL | 3.9953 mL | |
| 15 mM | 0.1065 mL | 0.5327 mL | 1.0654 mL | 2.6636 mL | |
| 20 mM | 0.0799 mL | 0.3995 mL | 0.7991 mL | 1.9977 mL | |
| 25 mM | 0.0639 mL | 0.3196 mL | 0.6393 mL | 1.5981 mL | |
| 30 mM | 0.0533 mL | 0.2664 mL | 0.5327 mL | 1.3318 mL | |
| 40 mM | 0.0400 mL | 0.1998 mL | 0.3995 mL | 0.9988 mL | |
| 50 mM | 0.0320 mL | 0.1598 mL | 0.3196 mL | 0.7991 mL | |
| 60 mM | 0.0266 mL | 0.1332 mL | 0.2664 mL | 0.6659 mL |