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Cat. No.: HY-P10077

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GL189

GL189 is a β-secretase inhibitor. GL189 has neuroprotective effect, and can be used for research of neurodegenerative diseases.

For research use only. We do not sell to patients.

CAS No.: 552337-94-7
Formula: C₄₄H₇₀N₁₀O₁₄
Molecular Weight:963.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GL189 Chemical Structure

CAS No.: 552337-94-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GL189 is a β-secretase inhibitor. GL189 has neuroprotective effect, and can be used for research of neurodegenerative diseases^[1].

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 552337-94-7
Molecular Weight 963.09
Formula C₄₄H₇₀N₁₀O₁₄
Sequence

Glu-Val-Asn-{Statine}-Val-Ala-Glu-Phe-NH2
Sequence Shortening

EVN-{Statine}-VAEF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yamamoto R, et al. Neuroprotective effects of beta-secretase inhibitors against rat retinal ganglion cell death. Neurosci Lett. 2004 Nov 3;370(1):61-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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GL189

All Beta-secretase Isoforms