Glyco-Obeticholic acid
Based on 1 Customer Validation
Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist.
For research use only. We do not sell to patients.
- Purity: 98.80%
- CAS No.: 863239-60-5
- Formula: C28H47NO5
- Molecular Weight:477.68
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 863239-60-5
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Appearance Solid
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Molecular Weight 477.68
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Formula C28H47NO5
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Color White to off-white
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SMILES
O=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (104.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0935 mL | 10.4673 mL | 20.9345 mL | 52.3363 mL |
| 5 mM | 0.4187 mL | 2.0935 mL | 4.1869 mL | 10.4673 mL | |
| 10 mM | 0.2093 mL | 1.0467 mL | 2.0935 mL | 5.2336 mL | |
| 15 mM | 0.1396 mL | 0.6978 mL | 1.3956 mL | 3.4891 mL | |
| 20 mM | 0.1047 mL | 0.5234 mL | 1.0467 mL | 2.6168 mL | |
| 25 mM | 0.0837 mL | 0.4187 mL | 0.8374 mL | 2.0935 mL | |
| 30 mM | 0.0698 mL | 0.3489 mL | 0.6978 mL | 1.7445 mL | |
| 40 mM | 0.0523 mL | 0.2617 mL | 0.5234 mL | 1.3084 mL | |
| 50 mM | 0.0419 mL | 0.2093 mL | 0.4187 mL | 1.0467 mL | |
| 60 mM | 0.0349 mL | 0.1745 mL | 0.3489 mL | 0.8723 mL | |
| 80 mM | 0.0262 mL | 0.1308 mL | 0.2617 mL | 0.6542 mL | |
| 100 mM | 0.0209 mL | 0.1047 mL | 0.2093 mL | 0.5234 mL |
Glyco-Obeticholic acid Related Classifications
HY-135400 Related Classifications
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