1. Anti-infection
  2. HCV
  3. HCV-IN-40

HCV-IN-40 

Cat. No.: HY-147764
Handling Instructions

HCV-IN-40 (Compound 18c) is a potent, orally active hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.259, 0.434 and 0.069 μM against GT1a, GT1b and GT1b CES1 replicons.

For research use only. We do not sell to patients.

HCV-IN-40 Chemical Structure

HCV-IN-40 Chemical Structure

CAS No. : 2087916-66-1

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Description

HCV-IN-40 (Compound 18c) is a potent, orally active hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.259, 0.434 and 0.069 μM against GT1a, GT1b and GT1b CES1 replicons[1].

IC50 & Target

EC50: 0.069 μM (GT1b CES1), 0.259 μM (GT1a), 0.434 μM (GT1b)[1]

In Vivo

HCV-IN-40 (Compound 18c) (1 mg/kg) provides very high nucleotide triphosphate (TP) in dog liver[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

594.32

Formula

C21H26BrFN3O9P

CAS No.
SMILES

CCOC(C(C)(N[[email protected]](OC[[email protected]]1O[[email protected]]([[email protected]@](Br)([[email protected]@H]1O)F)N2C=CC(NC2=O)=O)(OC3=CC=CC=C3)=O)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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HCV-IN-40
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