hsa-let-7b-5p antagomir
Based on 1 Customer Validation
hsa-let-7b-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Purity: 94.52%
- Molecular Weight:7236.76
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 7236.76
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Color White to yellow
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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miRBase Accession Number
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Mature miRNA Sequence
UGAGGUAGUAGGUUGUGUGGUU
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Stem-loop ID
hsa-let-7b
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Stem-loop Sequence
CGGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCUCGGAAGAUAACUAUACAACCUACUGCCUUCCCUG
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Species
Human, Mouse, Rat, Alligator mississippiensis, Astatotilapia burtoni, Bovine, Callithrix jacchus, Chicken, Chrysemys picta, Cricetulus griseus, Cyprinus carpio, Dasypus novemcinctus, Daubentonia madagascariensis, Dog, Fugu rubripes, Goat, Guinea pig, Metriaclima zebra, Microcebus murinus, Monodelphis domestica, Neolamprologus brichardi, Ophiophagus hannah, Oreochromis niloticus, Ornithorhynchus anatinus, Otolemur garnettii, Pan paniscus, Pan troglodytes, Papio hamadryas, Paralichthys olivaceus, Pongo pygmaeus, Pundamilia nyererei, Python bivittatus, Rabbit, Rhesus monkey, Saimiri boliviensis, Salmo salar, Taeniopygia guttata, Tetraodon nigroviridis, Zebrafish
Purity & Documentation
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Data Sheet (230 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)