hsa-let-7c-3p antagomir
hsa-let-7c-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Molecular Weight:7493.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 7493.89
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
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miRBase Accession Number
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Mature miRNA Sequence
CUGUACAACCUUCUAGCUUUCC
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Stem-loop ID
hsa-let-7c
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Stem-loop Sequence
GCAUCCGGGUUGAGGUAGUAGGUUGUAUGGUUUAGAGUUACACCCUGGGAGUUAACUGUACAACCUUCUAGCUUUCCUUGGAGC
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Species
Human, Mouse, Rat, Alligator mississippiensis, Anolis carolinensis, Chicken, Chrysemys picta, Columba livia, Cricetulus griseus, Dasypus novemcinctus, Goat, Guinea pig, Ophiophagus hannah, Ornithorhynchus anatinus, Paralichthys olivaceus, Pteropus alecto, Python bivittatus, Rabbit, Rhesus monkey, Salmo salar, Taeniopygia guttata, Xenopus laevis, Zebrafish
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)