mGluR2 modulator 5
mGluR2 modulator 5 (Compound 11) is an orally active, selective mGluR2 negative allosteric modulator with an IC50 of 8.9 nM. Pharmacokinetic studies in rats show that mGluR2 modulator 5 can effectively cross the blood-brain barrier. It can modulate cognitive and neurological functions in mood disorders and is suitable for research in the field of neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 1639898-35-3
- Formula: C20H17F3N4O
- Molecular Weight:386.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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mGluR2 8.9 nM (IC50) |
Chemical Information
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CAS No. 1639898-35-3
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Molecular Weight 386.37
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Formula C20H17F3N4O
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SMILES
CC1=NC=CC(C2=C(C(N(C3=CC=C(C(F)(F)F)C=C3)C[C@@H]4C)=O)N4N=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mGluR2 modulator 5 Related Classifications
HY-168028 Related Classifications
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