PAD-IN-3
PAD-IN-3 (Compound 16) is a potent dual peptidyl arginine deiminases 4 (PAD4) and PAD1 inhibitor with IC50 values of 0.204 μM and 0.273 μM, respectively. PAD-IN-3 is promising for research of citrullination-associated disorders such as cancer and autoimmune diseases.
For research use only. We do not sell to patients.
- Formula: C25H27ClN4O3
- Molecular Weight:466.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Molecular Weight 466.96
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Formula C25H27ClN4O3
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SMILES
OC1=CC2=C(C=C1)C=CC(C(N[C@@H](CCCNC(CCl)=N)C(NCC3=CC=CC=C3)=O)=O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAD-IN-3 Related Classifications
HY-174349 Related Classifications
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