SHMT-IN-4
SHMT-IN-4 (Compound 9ay) is a herbicide that targets and inhibits serine hydroxymethyltransferase (SHMT1) with an IC50 value of 193.8 g a.i./ha (active ingredient content per hectare). SHMT-IN-4 interferes with amino acid synthesis and metabolism in plants by binding to SHMT1, thereby inhibiting plant growth. Additionally, SHMT-IN-4 shows no significant toxicity to maize and honeybees.
For research use only. We do not sell to patients.
- CAS No.: 3014814-72-0
- Formula: C24H25BrClN3O7
- Molecular Weight:582.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 193.8 g a.i./ha (SHMT1)[1]
Chemical Information
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CAS No. 3014814-72-0
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Molecular Weight 582.83
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Formula C24H25BrClN3O7
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SMILES
O=C(OC)C1=CC(NC(CN2CCN(C(COC3=CC=C(Br)C=C3Cl)=O)CC2)=O)=C(C(OC)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)