DDO-02267
DDO-02267 is a selective and lysine-targeting covalent inhibitor of ALKBH5, with an IC50 value of 0.49 μM. DDO-02267 increases N6-methyladenosine (m6A) levels and targets the ALKBH5-AXL signaling axis. DDO-02267 can serve as a probe for investigating the biological function of mRNA demethylase.
For research use only. We do not sell to patients.
- CAS No.: 2919768-58-2
- Formula: C18H12N2O7S
- Molecular Weight:400.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ALKBH5: 0.49 μM, ALKBH3: 11.71 μM, FTO: 14.16 μM
Chemical Information
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CAS No. 2919768-58-2
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Molecular Weight 400.36
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Formula C18H12N2O7S
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SMILES
O=CC1=C(O)C2=C(C=CC=C2)C(S(=O)(NC(C3=NC=CC(C(O)=O)=C3)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DDO-02267 Related Classifications
HY-170668 Related Classifications
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