19(S)-HETE
19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 115461-40-0
- 分子式: C20H32O3
- 分子量:320.47
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-130309
(±)8(9)-EpETE -
HY-130140
8,9-DiHETE -
HY-130138C
5,6-DiHETE -
HY-121758
2-Hydroxyicosanoic acid -
HY-113516
20-HETE Ethanolamide -
HY-165005
14S(15R)-EET methyl ester -
HY-121987A
(±)15-HEDE -
HY-117044A
(±)12-HEPE -
HY-N7801
(±)5-HEPE -
HY-145546
14(15)-EpETE -
HY-165024
(±)5(6)-Epete methyl ester -
HY-165022
(±)14(15)-EpEDE
生物活性
製品説明
体外実験
19(S)-HETE (1 μM; 15 min) dose-dependently induces cAMP in MEG-01 cells with an EC50 value of 520 nM[1]. 19(S)-HETE (1 μM-1 M) dose-dependently activates the IP receptor with an EC50 value of 567 nM[1]. 19(S)-HETE (10 μM-1 M) displaces 3H-iloprost of IP receptor expressed COS-1 cells with a Ki value of 660 nM[1]. 19(S)-HETE (3 μM) relaxes arterial blood vessels and inhibits platelet activation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 115461-40-0
-
分子量 320.47
-
分子式 C20H32O3
-
SMILES
C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
19(S)-HETE 関連分類
HY-142972 関連分類
Powered by Bioz