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製品番号: HY-159096

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Apoptosis inducer 21

Apoptosis inducer 21 (Compound 5h) inhibits the proliferation of lung cancer cell H69AR with an IC₅₀ of 1.58 μM. Apoptosis inducer 21 arrests the cell cycle at G0/G1 phase, induces apoptosis in H69AR.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₃₈H₂₉Br₂NO₆
分子量:755.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Apoptosis inducer 21 構造式

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	21.19 μM Compound: 5h	Antiproliferative activity against human A549 cells by SRB assay Antiproliferative activity against human A549 cells by SRB assay	[PMID: 38964518]
H69AR	IC₅₀	1.58 μM Compound: 5h	Antiproliferative activity against human NCI-H69AR cells by SRB assay Antiproliferative activity against human NCI-H69AR cells by SRB assay	[PMID: 38964518]
NCI-H358	IC₅₀	35.82 μM Compound: 5h	Antiproliferative activity against human NCI-H358 cells by SRB assay Antiproliferative activity against human NCI-H358 cells by SRB assay	[PMID: 38964518]

化学情報

分子量 755.45
分子式 C₃₈H₂₉Br₂NO₆
SMILES

CC1=C(O)C(CC(N2)=C(CC3=C(O)C(C(C4=CC=C(Br)C=C4)=O)=CC(C)=C3O)C5=C2C=CC=C5)=C(O)C(C(C6=CC=C(Br)C=C6)=O)=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lin J, et al., Synthesis and biological evaluation of novel penindolone derivatives as potential antiproliferative agents against SCLC in vitro. Bioorg Med Chem Lett. 2024 Jul 2;110:129877. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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分子量分子量

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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