DCI-Br-3
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C25H20BrN3O2
- 分子量:474.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
DCI-Br-3 (0-20 μM; 30 min; SH-SY5Y cells) increases intracellular fluorescence in a concentration-dependent manner and has a good response to thiols in SH-SY5Y cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice (6 weeks of age)[1]
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Dosage:5 mg/kg
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Administration:intraperitoneal injection
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Result:Crossed the blood−brain barrier and had red fluorescence in BALB/c mice.
Emission (Em)
675
Excitation (Ex)
537
化学情報
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分子量 474.35
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分子式 C25H20BrN3O2
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SMILES
N#C/C(C#N)=C1CC(C)(C)CC(/C=C/C2=CC=C(OC(C3=CC=NC=C3)=O)C(Br)=C2)=C\1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)