FGFR3-IN-10
Based on 1 publication(s) in Google Scholar
FGFR3-IN-10 is a FGFR3 inhibitor with an IC50 of <350 nM. FGFR3-IN-10 is applicable to research related to cancer, systemic sclerosis, fibrosis, achondroplasia, thanatophoric dysplasia, and Muenke syndrome.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2833703-74-3
- 分子式: C23H22ClFN8O2
- 分子量:496.92
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 FGFR3-IN-10
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生物活性
製品説明
IC50 & Target
[1]|
FGFR3 <350 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.93 μM
Compound: 3
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Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISA
Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISA
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[PMID: 31153805] |
体外実験
FGFR3-IN-10 (Example 46) inhibits the kinase activity of fibroblast growth factor receptor 3 (FGFR3) in FGFR3 enzyme inhibition assays, with an IC50 < 350 nM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2833703-74-3
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分子量 496.92
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分子式 C23H22ClFN8O2
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SMILES
OC[C@H](C1=CC=C(C=N1)F)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=N3)C)=CN5C2=C(Cl)C=N5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
FGFR3-IN-10 関連分類
HY-122833 関連分類
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