Gapdhs - glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Gene

Also Known as Gapds; Gapd-s

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 14447

Summary

Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Human ortholog(s) of this gene implicated in Alzheimer's Disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Apr 2022]

Gapdhs Products (2)

mRNA Protein Name
NM_001290631.1 NP_001277560.1 glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 1
NM_008085.2 NP_032111.1 glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 2
Molecular Function GO Annotation Evidence 参考文献 由来
enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IDA
IDA: Inferred from direct assay
15546993 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
15546993 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
15546993 MGI
acts upstream of or within glycolytic process IMP
IMP: Inferred from mutant phenotype
15546993 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in cilium IDA
IDA: Inferred from direct assay
16687649 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
15546993 MGI
located in sperm fibrous sheath IDA
IDA: Inferred from direct assay
16687649 MGI
located in sperm principal piece IDA
IDA: Inferred from direct assay
9510974 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glyceraldehyde-3-phosphate dehydrogenase, testis-specific

  • GAPDH-2

  • spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2

  • spermatogenic glyceraldehyde-3-phosphate dehydrogenase

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Gapdhs NCBI NCBI:26330