Nrf1 - nuclear respiratory factor 1 Gene
Also Known as D6Ertd415e
生物種: Mus musculus
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within mitochondrion organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; connective tissue; genitourinary system; otic capsule; and skeleton. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Nrf1 Products (25)
| mRNA | Protein | Name |
|---|---|---|
| NM_001164226.2 | NP_001157698.1 | nuclear respiratory factor 1 isoform a |
| NM_001164227.2 | NP_001157699.1 | nuclear respiratory factor 1 isoform b |
| NM_001164228.2 | NP_001157700.1 | nuclear respiratory factor 1 isoform c |
| NM_001164229.2 | NP_001157701.1 | nuclear respiratory factor 1 isoform d |
| NM_001164230.2 | NP_001157702.1 | nuclear respiratory factor 1 isoform e |
| NM_001361692.2 | NP_001348621.1 | nuclear respiratory factor 1 isoform b |
| NM_001361693.2 | NP_001348622.1 | nuclear respiratory factor 1 isoform f |
| NM_001361694.2 | NP_001348623.1 | nuclear respiratory factor 1 isoform a |
| NM_001361695.2 | NP_001348624.1 | nuclear respiratory factor 1 isoform a |
| NM_001410221.1 | NP_001397150.1 | nuclear respiratory factor 1 isoform g |
| NM_001410222.1 | NP_001397151.1 | nuclear respiratory factor 1 isoform g |
| NM_001410223.1 | NP_001397152.1 | nuclear respiratory factor 1 isoform b |
| NM_001410224.1 | NP_001397153.1 | nuclear respiratory factor 1 isoform b |
| NM_001410225.1 | NP_001397154.1 | nuclear respiratory factor 1 isoform d |
| NM_001410226.1 | NP_001397155.1 | nuclear respiratory factor 1 isoform e |
| NM_001410227.1 | NP_001397156.1 | nuclear respiratory factor 1 isoform f |
| NM_001410228.1 | NP_001397157.1 | nuclear respiratory factor 1 isoform f |
| NM_001410229.1 | NP_001397158.1 | nuclear respiratory factor 1 isoform h |
| NM_001410230.1 | NP_001397159.1 | nuclear respiratory factor 1 isoform h |
| NM_001410231.1 | NP_001397160.1 | nuclear respiratory factor 1 isoform i |
| NM_001410232.1 | NP_001397161.1 | nuclear respiratory factor 1 isoform j |
| NM_001410233.1 | NP_001397162.1 | nuclear respiratory factor 1 isoform j |
| NM_001410234.1 | NP_001397163.1 | nuclear respiratory factor 1 isoform k |
| NM_001410235.1 | NP_001397164.1 | nuclear respiratory factor 1 isoform k |
| NM_010938.5 | NP_035068.3 | nuclear respiratory factor 1 isoform a |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
26231763 | MGI |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| acts upstream of or within mitochondrion organization |
IMP
IMP: Inferred from mutant phenotype
|
11134350 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
nuclear respiratory factor 1 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-129225 | WRR139 | Inhibitor | 99.71% | Unkown |
| HY-149127 | Rosolutamide | 99.03% | Unkown | |
| HY-RS09567 | NRF1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-125535 | OSU-53 | / | Unkown | |
| HY-184160 | Mcl1 Degrader-1 | / | Unkown | |
| HY-RS09244 | NFE2L1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17333 | Nrf1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21165 | Nfe2l1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23788 | Nrf1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service