Tsg101 - tumor susceptibility 101 Gene

Also Known as Rw

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 292925

Summary

Enables nuclear receptor coactivator activity. Involved in endosome to lysosome transport and protein monoubiquitination. Located in endosome membrane and nucleus. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and Prostate Cancer. Orthologous to human TSG101 (tumor susceptibility 101). [provided by Alliance of Genome Resources, Apr 2022]

Tsg101 Products (1)

mRNA Protein Name
NM_181628.2 NP_853659.2 tumor susceptibility gene 101 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables nuclear receptor coactivator activity IDA
IDA: Inferred from direct assay
14761944 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
19808888 RGD
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
14761944 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in endosome membrane IDA
IDA: Inferred from direct assay
11134028 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor susceptibility gene 101 protein

  • ESCRT-I complex subunit TSG101

  • Tumor supressor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-17421 Tenatoprazole Inhibitor 99.80% Unkown
HY-RS15142 TSG101 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19082 Tsg101 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P10845 KRL74 Inhibitor / Unkown
HY-RS25573 Tsg101 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
阻害性抗体 (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-P991414 FGI-1011A6 Inhibitor / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Tsg101 NCBI NCBI:7251