NS5818
NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potential for the research of osteoporosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 674299-39-9
- 分子式: C23H19Cl2N7O2
- 分子量:496.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
NS5818 (50 µM; 6 days) inhibits acidification of the osteoclastic resorption compartment and bone resorption with an IC50 value of 5µM for bone resorption in human osteoclasts[1].
NS5818 (10 µM; 20 days) inhibits resorption in mature osteoclasts cultured on bovine bone slices[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 674299-39-9
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分子量 496.35
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分子式 C23H19Cl2N7O2
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SMILES
O=C(C1=CC=C(C=C1)C2=CC=C(C=C2C3=NNN=N3)NC(NC4=CC(Cl)=CC(Cl)=C4)=O)N(C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NS5818 関連分類
HY-122077 関連分類
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