country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-139111

Copy Link Print Information

Oxocarbazate

Oxocarbazate is an inhibitor of human cathepsin L with the IC₅₀ values of 6.9 nM (human Cathepsin L,0 h) 0.4 nM ((human Cathepsin L,4 h) and 5.07 μM (human cathepsin B), respectively. Oxocarbazate blockes both SARS-CoV (IC₅₀ = 273 nM) and Ebola virus (IC₅₀ = 193 nM) entry into 293T cells.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1014405-03-8
分子式: C₂₈H₃₃N₅O₆
分子量:535.59

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Oxocarbazate 構造式

CAS 番号: 1014405-03-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cathepsin アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	IC₅₀	193 μM Compound: 44; CID 23631927	Antiviral activity against Ebolavirus infected in HEK293T cells assessed as reduction in viral replication incubated for 7 hrs by luciferase assay Antiviral activity against Ebolavirus infected in HEK293T cells assessed as reduction in viral replication incubated for 7 hrs by luciferase assay	[PMID: 33486200]
HEK-293T	IC₅₀	273 μM Compound: 44; CID 23631927	Antiviral activity against SARS-CoV infected in HEK293T cells assessed as reduction in viral replication incubated for 7 hrs by luciferase assay Antiviral activity against SARS-CoV infected in HEK293T cells assessed as reduction in viral replication incubated for 7 hrs by luciferase assay	[PMID: 33486200]

化学情報

CAS 番号 1014405-03-8
分子量 535.59
分子式 C₂₈H₃₃N₅O₆
SMILES

O=C(N1C2=CC=CC=C2CCC1)COC(NNC([C@@H](NC(OC(C)(C)C)=O)CC3=CNC4=CC=CC=C34)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Shah PP, et al. A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. Mol Pharmacol. 2010;78(2):319-324. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ