ppTG21
ppTG21 is an endosomolytic agent and inducer. ppTG21 can facilitate endosomal escape of Cas9-2lig-1NLS and Cas9-ASGPrL ribonucleoproteins (RNPs) to enable receptor-facilitated, cell-type specific gene editing in cancer cells without electroporation or transfection reagents. ppTG21 can be used for the research of gene editing.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 380480-77-3
- 分子式: C115H173N31O22
- 分子量:2341.80
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
ppTG21 (7.5 nmol ppTG21 salt; 44-48 h) facilitates endosomal escape of Cas9-2lig-1NLS RNP, leading to cell-type specific gene editing with 4.8% indels in HEPG2 cells (ASGPr+); negligible editing occurs in SKHEP cells (ASGPr diminished) with either RNP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 380480-77-3
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分子量 2341.80
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分子式 C115H173N31O22
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配列
Gly-Leu-Phe-His-Ala-Leu-Leu-His-Leu-Leu-His-Ser-Leu-Trp-His-Leu-Leu-Leu-His-Ala
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シーケンスの短縮
GLFHALLHLLHSLWHLLLHA
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
ppTG21 関連分類
HY-P11639 関連分類
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