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製品番号: HY-N3564A

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(Rac)-Centrolobol

(Rac)-Centrolobol is a racemic isomer of Centrolobol (HY-N3564). Centrolobol is a diarylheptane compound with antioxidant and anti-inflammatory properties, which exists in the fermented stems of Alnus sibirica. Centrolobol scavenges DPPH free radicals and inhibits the production of NO in LPS-stimulated immune cells. Centrolobol can be used in studies related to anti-inflammation and antioxidation.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 98119-94-9
分子式: C₁₉H₂₄O₃
分子量:300.39

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

(Rac)-Centrolobol 構造式

CAS 番号: 98119-94-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Centrolobol (compound 12) inhibits nitric oxide production in LPS-stimulated RAW 264.7 cells, with an IC₅₀ value of 27.77 μM^[1].
Centrolobol inhibits the production of DPPH, with an IC₅₀ value of 44.4 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 98119-94-9
分子量 300.39
分子式 C₁₉H₂₄O₃
SMILES

OC1=CC=C(CCCCC(CCC2=CC=C(C=C2)O)O)C=C1
Structure Classification
- Phenols
- Polyphenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Le TT, et al. Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis. Molecules, 2017, 22(9):1566.

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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