Centrolobol
Centrolobol is a diarylheptane compound with antioxidant and anti-inflammatory properties, which exists in the fermented stems of Alnus sibirica. Centrolobol scavenges DPPH free radicals and inhibits the production of NO in LPS-stimulated immune cells. Centrolobol can be used in studies related to anti-inflammation and antioxidation.
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- CAS. Nr.: 30359-01-4
- Formel: C19H24O3
- Molecular Weight:300.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| Macrophage | IC50 |
73 μM
Compound: 8
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Inhibition of LPS-induced NO production in ddY mouse peritoneal macrophages by Griess reagent method
Inhibition of LPS-induced NO production in ddY mouse peritoneal macrophages by Griess reagent method
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[PMID: 12542351] |
| RAW264.7 | IC50 |
27.8 μM
Compound: 67
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
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[PMID: 33422907] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 30359-01-4
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Molecular Weight 300.39
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Formel C19H24O3
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SMILES
OC(C=C1)=CC=C1CCCC[C@@H](O)CCC2=CC=C(O)C=C2
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Centrolobol Related Classifications
HY-N3564 Related Classifications
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