JXL066
JXL066 is a covalent mitochondrial pyruvate carrier (MPC) inhibitor that promotes hair growth by blocking the transport of Pyruvic acid (HY-Y0781) into mitochondria, thereby redirecting cytoplasmic pyruvate toward Lactic acid (HY-B2227) production. JXL066 can be used for research on hair loss.
For research use only. We do not sell to patients.
- CAS No.: 2260696-60-2
- Formula: C23H15F7N2O2
- Molecular Weight:484.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
JXL066 (10 μM; 24-30 h) promotes cellular lactate production in MCF10A cells, exhibiting similar potency to its corresponding carboxylic acid analogue JXL052[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2260696-60-2
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Molecular Weight 484.37
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Formula C23H15F7N2O2
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SMILES
CCOC(/C(C#N)=C/C1=CN(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C3=CC=CC(F)=C13)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)