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Cat. No.: HY-N10542

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Aplyronine C

Aplyronine C is an active compound. Aplyronine C shows potent antitumor activity and has cytotoxicity against HeLa-S3 cells with an IC₅₀ values of 22 nM. Aplyronine C can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 151923-86-3
Formula: C₅₃H₉₀N₂O₁₂
Molecular Weight:947.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Aplyronine C Chemical Structure

CAS No.: 151923-86-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

IC50: 22 nM (HeLa-S3 cells)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa S3	IC₅₀	17 nM Compound: 2	Cytotoxicity against human HeLa S3 cells assessed as reduction in cell viability measured after 96 hrs by MTT assay Cytotoxicity against human HeLa S3 cells assessed as reduction in cell viability measured after 96 hrs by MTT assay	[PMID: 27161875]

In Vitro

Aplyronine C has cytotoxicity of aplyronines against HeLa-S3 cells with an IC₅₀ values of 2.9 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 151923-86-3
Molecular Weight 947.29
Formula C₅₃H₉₀N₂O₁₂
SMILES

O=CN(C)/C=C/[C@@H](C)[C@@H](OC(C)=O)[C@@H](C)[C@H](OC([C@H](C)N(C)C)=O)CC[C@H](C)[C@H](O)[C@@H]([C@]1([H])C/C=C/[C@@H](C[C@@H](C/C=C([C@H](CC[C@H]([C@H]([C@@H]([C@@H](C/C=C/C=C/C(O1)=O)O)C)O)C)OC)\C)C)OC)C
Structure Classification
- Alkaloids
- Others
Initial Source
- Animals
Aplysia kurodai
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Makoto Ojika, et al. Aplyronines D–H from the sea hare Aplysia kurodai: isolation, structures, and cytotoxicity. , 68(4), 982–987. doi:10.1016/j.tet.2011.11.095

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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