FolB-IN-1
FolB-IN-1 (Compound 3e) is an inhibitor of FolB that can suppress the activity of FolB enzyme from Mycobacterium tuberculosis (MtFolB). FolB-IN-1 exhibits antimycobacterial activity with an MIC value of 40 µg/mL (108 µM).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C17H18N6O2S
- 분자량:370.43
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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분자량 370.43
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화학식 C17H18N6O2S
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SMILES
O=C(NC1=C2CCCCC2=CC=C1)CSC3=NC4=C(N=C(N)NC4=O)N3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Czeczot A M, et al. Crystal structure of dihydroneopterin aldolase from Mycobacterium tuberculosis associated with 8-mercaptoguanine, and development of novel S8-functionalized analogues as inhibitors: Synthesis, enzyme inhibition, in vitro toxicity and antitubercular activity[J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2024, 39(1): 2388207. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)