Icatibant (Standard)
Icatibant (Standard) is the analytical standard of Icatibant. This product is intended for research and analytical applications. Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98%
- CAS No.: 130308-48-4
- 화학식: C59H89N19O13S
- 분자량:1304.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-17446
IcatibantBradykinin Receptor Antagonist -
HY-15043
ELN-441958Bradykinin B1 Receptor Antagonist -
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SSR240612 -
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R715Bradykinin B1 Receptor Antagonist -
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HY-103291
Sar-[D-Phe8]-des-Arg9-BradykininB1 Receptor Agonist -
HY-108896
Icatibant acetateBradykinin B2 Antagonist -
HY-103289
MEN 11270B2 Kinin Receptor Antagonist -
HY-105155
LobradimilBradykinin B2 Receptor Agonist -
HY-P1469
Bradykinin (1-6)Bradykinin Receptor Modulator -
HY-P1488
Bradykinin (1-5)PAR-1/PAR-4 Inhibitor -
HY-P4676
Lys-(Des-Arg9,Leu8)-BradykininBradykinin Receptor Antagonist
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 130308-48-4
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분자량 1304.52
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화학식 C59H89N19O13S
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SMILES
[H][C@]1(C[C@@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)N2C([C@@H]3N(C([C@H](CO)NC([C@H](CC4=CC=CS4)NC(CNC([C@@H]5C[C@@H](O)CN5C([C@H]6N(C([C@H](CCCNC(N)=N)NC([C@H](N)CCCNC(N)=N)=O)=O)CCC6)=O)=O)=O)=O)=O)CC7=C(C=CC=C7)C3)=O)[C@]2([H])CCCC1
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Synonyms
HOE 140 (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Hock FJ, et al. Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies. Br J Pharmacol. 1991 Mar;102(3):769-73. [Content Brief]
[2]. Y Arai, et al. Effect of Icatibant, a Bradykinin B2 Receptor Antagonist, on the Development of Experimental Ulcerative Colitis in Mice. Dig Dis Sci. 1999 Apr;44(4):845-51. [Content Brief]
[3]. Marie-Thérèse Bawolak, et al The Bradykinin B2 Receptor Antagonist Icatibant (Hoe 140) Blocks Aminopeptidase N at Micromolar Concentrations: Off-Target Alterations of Signaling Mediated by the Bradykinin B1 and Angiotensin Receptors. Eur J Pharmacol. 2006 Dec 3;551(1-3):108-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Icatibant (Standard) Related Classifications
HY-17446R Related Classifications
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