JAK/HDAC-IN-4

JAK/HDAC-IN-4 (compound 11 i) is a JAK/HDAC inhibitor with the IC50 values of 0.49 nM and 12 nM for JAK2 and HDAC6, respectively. JAK/HDAC-IN-4 inhibits the cell proliferation and the production of nitric oxide. JAK/HDAC-IN-4 ameliorates psoriasis-like skin lesions in an Imiquimod (HY-B0180)-induced murine model with low toxicity.

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  • CAS No.: 3064994-08-4
  • 화학식: C30H32N8O5S
  • 분자량:616.69
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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