L-736380

L-736380 is a high affinity CCK-B (cholecystokinin B receptor) receptor antagonist, with IC50 values of 0.054 nM and 400 nM for CCK-B and CCK-A, respectively. L-736380 dose-dependently inhibits gastric acid secretion in anesthetized rats (ID50, 0.064 mg/kg) and ex vivo binding of [125I]CCK-8S in BKTO mice brain membranes (ED50, 1.7 mg/kg).

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  • CAS No.: 152885-49-9
  • 화학식: C25H29N9O2
  • 분자량:487.56
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Cholecystokinin Receptor Isoforms

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