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United States

Product Name	Size / Unit Price	Qty

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Cat. No.: HY-169176

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LpxC-IN-15

LpxC-IN-15 ((S)-13j) is a potent LpxC inhibitor with K_i values of 9.05, 5.6 nM for EcLpxC C63A, PaLpxC, respectively. LpxC-IN-15 shows antibacterial activity.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₂H₃₂N₄O₅
분자량:552.62

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

LpxC-IN-15 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

LpxC-IN-15 ((S)-13j) is a potent LpxC inhibitor with K_i values of 9.05, 5.6 nM for EcLpxC C63A, PaLpxC, respectively. LpxC-IN-15 shows antibacterial activity^[1].

IC₅₀ & Target

K_i: 9.05 nM (EcLpxC C63A); 5.6 nM (PaLpxC)^[1]

Chemical Information

분자량 552.62
화학식 C₃₂H₃₂N₄O₅
SMILES

O=C(NO)[C@@H](OCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)CN3CCOCC3)CNC(C4=CC(C=CN5)=C5C=C4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mielniczuk S, et al. Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. J Med Chem. 2024 Oct 10;67(19):17363-17391. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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