RP 72540
RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors.
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- CAS No.: 139088-45-2
- 화학식: C28H30N4O6
- 분자량:518.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 139088-45-2
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분자량 518.56
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화학식 C28H30N4O6
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SMILES
O=C(N(C1=CC=CC(OC)=C1)CC(N(C)C2=CC=CC=C2)=O)CNC(NC3=CC=CC(C(C(O)=O)C)=C3)=O
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Synonyms
RPR101048
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)