Lanisidenib
Lanisidenib is the inhibitor for isocitrate dehydrogenase that exhibits antineoplastic activity.
For research use only. We do not sell to patients.
- CAS No.: 2135537-20-9
- Formula: C28H23ClF3N5O4S
- Molecular Weight:618.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-87MG ATCC | IC50 |
<20 nM
Compound: 69
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Inhibition of IDH1 RI32C mutant in human U87 cells assessed as reduction in intracellular 2-HG levels after 24 hrs by resazurin fluorescence based assay
Inhibition of IDH1 RI32C mutant in human U87 cells assessed as reduction in intracellular 2-HG levels after 24 hrs by resazurin fluorescence based assay
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[PMID: 29847930] |
Chemical Information
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CAS No. 2135537-20-9
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Molecular Weight 618.03
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Formula C28H23ClF3N5O4S
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SMILES
FC(F)(C1)CC1NC([C@H](C2=C(C=CC=C2)Cl)N(C3=CC(F)=CC=C3)C([C@H]4N(C5=CC(C#N)=CC=N5)S(=O)(CC4)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lanisidenib Related Classifications
HY-168980 Related Classifications
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