Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
Based on 1 Customer Validation
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A).
For research use only. We do not sell to patients.
- Purity : 99.82%
- CAS No.: 1638970-46-3
- Formula: C67H101N11O16
- Molecular Weight:1316.58
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1638970-46-3
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Appearance Solid
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Molecular Weight 1316.58
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Formula C67H101N11O16
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Color White to off-white
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SMILES
C[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CC(N)=O)NC([C@H](C)NC([C@H](C)NC(CCCCCN(C4=O)C(C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (75.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7595 mL | 3.7977 mL | 7.5954 mL | 18.9886 mL |
| 5 mM | 0.1519 mL | 0.7595 mL | 1.5191 mL | 3.7977 mL | |
| 10 mM | 0.0760 mL | 0.3798 mL | 0.7595 mL | 1.8989 mL | |
| 15 mM | 0.0506 mL | 0.2532 mL | 0.5064 mL | 1.2659 mL | |
| 20 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9494 mL | |
| 25 mM | 0.0304 mL | 0.1519 mL | 0.3038 mL | 0.7595 mL | |
| 30 mM | 0.0253 mL | 0.1266 mL | 0.2532 mL | 0.6330 mL | |
| 40 mM | 0.0190 mL | 0.0949 mL | 0.1899 mL | 0.4747 mL | |
| 50 mM | 0.0152 mL | 0.0760 mL | 0.1519 mL | 0.3798 mL | |
| 60 mM | 0.0127 mL | 0.0633 mL | 0.1266 mL | 0.3165 mL |
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE Related Classifications
HY-147204 Related Classifications
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