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Cat. No.: HY-185845

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MC-VC-PAB-PEG4-DBCO

MC-VC-PAB-PEG4-DBCO is a protease-cleavable ADC linker composed of Mc-VC-PAB and PEG4-DBCO moieties.

For research use only. We do not sell to patients.

Formula: C₅₈H₇₅N₉O₁₄
Molecular Weight:1122.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MC-VC-PAB-PEG4-DBCO Chemical Structure

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Use of MCE Products

One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

Description

MC-VC-PAB-PEG4-DBCO is a protease-cleavable ADC linker composed of Mc-VC-PAB and PEG4-DBCO moieties^[1].

All ADC Linkers Isoforms :

Chemical Information

Molecular Weight 1122.27
Formula C₅₈H₇₅N₉O₁₄
SMILES

O=C(CCOCCOCCOCCOCCNC(OCC(C=C1)=CC=C1NC([C@@H](NC([C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)NCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yu SF, et al. A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Jul 15;21(14):3298-306. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
Chemical Information
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MC-VC-PAB-PEG4-DBCO

All ADC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MC-VC-PAB-PEG4-DBCO Related Classifications

HY-185845 Related Classifications